Pleural effusion from metastatic breast cancer

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Breast cancer relapse remains a common cause of morbidity and mortality in patients who undergo initial treatment with surgery and with or without concurrent chemotherapy or radiation. Relapse rates remain high within the first decade after initial treatment, after which the risk of relapse decreases. Here, we present two uncommon cases of delayed breast cancer relapses with pleural metastasis, which caused MPEs.

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A year-old male with a plus pack-year smoking history and known chronic obstructive pulmonary disease presents with dyspnea on exertion and a nonproductive cough of 3 weeks duration. He has associated symptoms of fatigue, anorexia, and a 15 lb weight loss. Chest radiograph reveals right upper lobe collapse and a moderate sized right-sided pleural effusion with no mediastinal shift.

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What is secondary breast cancer in the lung? Newly diagnosed or worried about a symptom? How do the lungs work?

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Skip to Content. A pleural effusion is a buildup of extra fluid in the space between the lungs and the chest wall. This area is called the pleural space.

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Instead, a tumor might be first discovered on an imaging study done as part of treatment follow-up, such as a chest CT computed tomography scan. Many doctors recommend that any unusual symptoms persisting for more than a week or two should be checked out. If your doctor suspects lung metastasis, he or she is likely to order imaging tests such as a chest CT or a PET positron emission tomography scan.

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Release date: February 1, Expiration date: January 31, Estimated time of completion: 1 hour. Malignant pleural effusion can be managed in different ways, including clinical observation, thoracentesis, placement of an indwelling pleural catheter, and chemical pleurodesis. The optimal strategy depends on a variety of clinical factors.

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Pleural effusion is an abnormal buildup of fluid in the pleural cavity. The pleural cavity is the space between the lungs and the chest wall. The fluid builds up between the 2 layers of the pleura, which is a thin layer of tissue that covers the lungs and lines the chest wall. When pleural effusion is related to cancer or there are cancer cells in the fluid, it may be called malignant pleural effusion.

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A malignant pleural effusion is a complication that involves the build-up of fluid containing cancer cells between the membranes that line the lungs. It occurs in around 30 percent of lung cancers, but can also occur with other cancers, such as breast cancer, ovarian cancer, leukemias, and lymphomas. With lung cancer, a malignant pleural effusion may be the first sign of cancer, or it can occur as a late complication of advanced lung cancer.

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Patients with a cancer diagnosis endure multiple complications and stresses, particularly when disease progresses. Unfortunately, the treatments themselves can also result in debilitating side effects that further increase their suffering. MPE is estimated to occur in aboutpeople with cancer per year in the United States. Each day, approximately 5 L or more of pleural fluid is produced and moves throughout the pleural space.


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